Automated research refresh updated the product evidence set.
Before: Evidence 53 · Safety 66 · Effectiveness 47 · Confidence 71
After: Evidence 53 · Safety 66 · Effectiveness 43 · Confidence 73
More calories. More protein.
Resar evidence panel
0–100 · cited research only
Evidence Score
53
Emerging
Safety Score
66
Good
Effectiveness Score
43
Emerging
Research Confidence
73
Strong
Product Fit Score
39
Limited
Bottom line
Limited evidence (Emerging) — treat claims cautiously and review sources directly.
Product fit is weaker — dose, price, or practical use may not align with what studies tested.

Evidence Score
53
Emerging
Price
$44.00
Resar may earn an affiliate commission on this purchase. Commissions never change scores — see our affiliate disclosure and conflicts policy. Scores reflect cited research, not medical advice.
Compare others in SupplementsTop research
Ranked by evidence hierarchy and how closely each study matches this product. Start with the strongest study, then read down. Every claim needs a trail.
Other · 2025
What the research shows
Highlights that higher quality protein intake is associated with better muscle mass retention and healthier weight trajectories in aging populations.
OR27: Supplementing Breakfast with A Vitamin D and Leucine-Enriched Whey Protein Medical Nutrition Drink Improves Postprandial Muscle Protein Synthesis and Muscle Mass in Healthy Older Adults
Other · Clinical Nutrition · 2016
Dietary Protein to Support Muscle Hypertrophy
Other · Nestlé Nutrition Institute Workshop Series · 2011
OP015 WHICH NUTRITIONAL PROTEIN STRATEGY TO RECOVER MUSCLE MASS AFTER PROLONGED IMMOBILIZATION DURING AGING?
Other · Clinical Nutrition Supplements · 2012
Students choosing fat-free chocolate milk during school lunch consume more calories, total sugar, protein, minerals and vitamins at lunch
Observational · Public Health Nutrition · 2021
Scores reflect these cited studies, not medical advice. Expand the full evidence detail below for protocols, dose context, and reported side effects.
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Claim ledger
Each product claim below is tied to a specific paper with study type, match strength, and limitations. Nothing here is medical advice — it is a research trail you can audit.
Claim match reflects how closely a specific paper supports this benefit — not AI confidence or medical certainty.
Full evidence detail
Each paper below is ranked for this listing. Start with the highest match, then expand any study for a plain-language readout.
How to read this section
In plain language
What the study reported
Verified extract — not AI generated
“Highlights that higher quality protein intake is associated with better muscle mass retention and healthier weight trajectories in aging populations.”
Suggested use aligns with typical label directions: consume the recommended serving(s) daily to meet increased protein needs.
No adverse effects reported in the review.
Caveats
Being a narrative review, it does not present new experimental data and relies on existing studies of varying quality.
Transparency
Human review is pending for this listing.
Automated research refresh updated the product evidence set.
Before: Evidence 53 · Safety 66 · Effectiveness 47 · Confidence 71
After: Evidence 53 · Safety 66 · Effectiveness 43 · Confidence 73
Reviews
4.5
average rating
34,766 Amazon reviews were available from the listing metadata.
Short answers from Resar's evidence model. Not medical advice — read the full study breakdown above.
Resar scores Optimum Nutrition Serious Mass, Weight Gainer Protein Powder, Mass Gainer, Vitamin C and Zinc for Immune Support, Creatine, Chocolate, 6 Pound (Packaging May Vary) 53/100 for evidence (Emerging grade), with Safety 66/100 and research confidence 73/100. Scores reflect indexed studies mapped to this listing, not marketing claims.
Resar indexes 5 research papers for Optimum Nutrition Serious Mass, Weight Gainer Protein Powder, Mass Gainer, Vitamin C and Zinc for Immune Support, Creatine, Chocolate, 6 Pound (Packaging May Vary), ranked by relevance to this product's ingredients, dose, and category. Open the study-by-study breakdown on this page for match percentages and summaries.
Limited evidence (Emerging) — treat claims cautiously and review sources directly.
Resar maps product claims to cited studies, grades evidence quality and product relevance, and surfaces safety and confidence sub-scores. Product fit is weaker — dose, price, or practical use may not align with what studies tested. See our methodology page for the full scoring framework.